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John G. Doench

Broad Institute
Massachusetts Institute of Technology

211

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16709

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UFMylation inhibits the proinflammatory capacity of interferon-γ-activated macrophages.

2021 Proceedings of the National Academy of Sciences of the United States of America
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A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition

2021 bioRxiv
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Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway.

2021 Cell
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Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin.

2021 Proceedings of the National Academy of Sciences of the United States of America
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Massively parallel assessment of human variants with base editor screens.

2021 Cell
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Whole-Genome CRISPR Screening Identifies N -Glycosylation As an Essential Pathway and a Potential Novel Therapeutic Target in CALR -Mutant MPN

2021 Blood
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Discovery of novel putative tumor suppressors from CRISPR screens reveals rewired lipid metabolism in AML cells

2021 bioRxiv
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Targeting oncoproteins with a positive selection assay for protein degraders.

2021 Science Advances
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Benchmarking of SpCas9 variants enables deeper base editor screens of BRCA1 and BCL2

2021 bioRxiv
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In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma

2021 Immunity
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Citations (7)