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Hualiang Jiang

Chinese Academy of Sciences
East China University of Science and Technology
ShanghaiTech University

892

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29555

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A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects.

2021 Drug Design Development and Therapy
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Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein.

2021 Acta Pharmacologica Sinica
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Glycan Epitopes and Potential Glycoside Antagonists of DC-SIGN Involved in COVID-19: In Silico Study

2021
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Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase.

2021 Acta Pharmacologica Sinica
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Drug Discovery and Development Targeting the Life Cycle of SARS-CoV-2

2021
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Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2.

2021 Proceedings of the National Academy of Sciences of the United States of America
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High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases.

2021 Nucleic Acids Research
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Generative Models for De Novo Drug Design.

2021 Journal of Medicinal Chemistry
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Reply to: Binding site for MDL-801 on SIRT6.

2021 Nature Chemical Biology
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Graph neural networks for automated de novo drug design.

2021 Drug Discovery Today
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