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Jun Liu

Genomics Institute of the Novartis Research Foundation

21

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3493

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Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling

2017 Annals of the Rheumatic Diseases
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Temporary, Systemic Inhibition of the WNT/β-Catenin Pathway promotes Regenerative Cardiac Repair following Myocardial Infarct

2016
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In vivo Wnt pathway inhibition of human squamous cell carcinoma growth and metastasis in the chick chorioallantoic model

2016 Journal of Otolaryngology-head & Neck Surgery
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Abstract IA35: Discovery of porcupine inhibitors targeting Wnt signaling in cancer

2016 Cancer Research
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Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors

2016 ACS Medicinal Chemistry Letters
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Abstract 2140: Dual Wnt and EGFR-MAPK dependency of BRAFV600E-mutant colorectal cancer

2015 Cancer Research
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Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein

2014 Cell Reports
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Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening

2014 BMC Cancer
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Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia

2013 Nature Genetics
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NSD2 is recruited through its PHD domain to oncogenic gene loci to drive multiple myeloma.

2013 Cancer Research
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