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Maria T. Diaz-Meco

Discovery Institute
Spanish National Research Council
Sanford-Burnham Institute for Medical Research

154

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24530

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Mouse model of colorectal cancer: orthotopic co-implantation of tumor and stroma cells in cecum and rectum

2021
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PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis

2021 Molecular Cell
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Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

2021 Cancer Cell
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NBR1 is a critical step in the repression of thermogenesis of p62-deficient adipocytes through PPARγ.

2021 Nature Communications
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The interplay between PRKCI/PKCλ/ι, SQSTM1/p62, and autophagy orchestrates the oxidative metabolic response that drives liver cancer.

2020 Autophagy
- Jorge Moscat
- Maria T. Diaz-Meco
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PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression.

2020 Cancer Cell
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NRF2 Activates Growth Factor Genes and Downstream AKT Signaling to Induce Mouse and Human Hepatomegaly.

2020 Journal of Hepatology
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The scaffold protein p62 regulates adaptive thermogenesis through ATF2 nuclear target activation

2020 Nature Communications
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Fructose stimulated de novo lipogenesis is promoted by inflammation.

2020
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An Orthotopic Implantation Mouse Model of Hepatocellular Carcinoma with Underlying Liver Steatosis

2020
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