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Wafik S. El-Deiry

University of Pennsylvania
Fox Chase Cancer Center
Penn State Cancer Institute

742

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Abstract 1205: Clinical and genomic features of advanced urothelial carcinoma with 9p21 deletion

2021
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Opposing effects of BRCA1 mRNA expression on patient survival in breast and colorectal cancer and variations among African American, Asian, and younger patients

2021 Oncotarget
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Potent preclinical sensitivity to imipridone-based combination therapies in oncohistone H3K27M-mutant diffuse intrinsic pontine glioma is associated with induction of the integrated stress response, TRAIL death receptor DR5, reduced ClpX and apoptosis

2021 American Journal of Cancer Research
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Anti-cancer efficacy including Rb-deficient tumors and VHL-independent HIF1α proteasomal destabilization by dual targeting of CDK1 or CDK4/6 and HSP90.

2021 Scientific Reports
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Integrating Molecular Biomarker Inputs Into Development and Use of Clinical Cancer Therapeutics.

2021 Frontiers in Pharmacology
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Abstract 2329: ONC212-induced impairment of oxidative phosphorylation is synergistic with glycolysis inhibition in treatment of pancreatic cancer in vitro and in vivo

2021
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ONC212 IS A NOVEL MITOCAN ACTING SYNERGISTICALLY WITH GLYCOLYSIS INHIBITION IN PANCREATIC CANCER

2021 Molecular Cancer Therapeutics
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Abstract 2676: GSK3β inhibition by small molecule 9-ING-41 decreases VEGF and other cytokines, and boosts NK and T cell-mediated killing of colorectal tumor cells

2021 Tumor Biology
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Abstract 2736: Decreasing colorectal cancer extracellular pH dampens immune cell killing and is partially ameliorated by treatment with NHE1 inhibitor Cariporide

2021 Tumor Biology
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Abstract 1044: ONC201 as a novel anti-cancer therapeutic via modulation of inhibitors of apoptosis and up-regulation of DR5 in gastric adenocarcinoma

2021
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