CD1D

4WO4, 1ZT4, 2PO6, 3HUJ, 3SDX, 3TZV, 3U0P, 3VWJ, 3VWK, 4EN3, 4LHU, 4MNG, 4MQ7, 4WW291212479ENSG00000158473ENSMUSG00000028076P15813P11609NM_001766NM_001319145NM_007639NP_001306074NP_001757NP_031665CD1D is the human gene that encodes the protein CD1d, a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are non-classical MHC proteins, related to the class I MHC proteins, and are involved in the presentation of lipid antigens to T cells. CD1d is the only member of the group 2 CD1 molecules.1zt4: The crystal structure of human CD1d with and without alpha-Galactosylceramide CD1D is the human gene that encodes the protein CD1d, a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are non-classical MHC proteins, related to the class I MHC proteins, and are involved in the presentation of lipid antigens to T cells. CD1d is the only member of the group 2 CD1 molecules. CD1d-presented lipid antigens activate a special class of T cells, known as natural killer T (NKT) cells, through the interaction with the T-cell receptor present on NKT membranes. When activated, NKT cells rapidly produce Th1 and Th2 cytokines, typically represented by interferon-gamma and interleukin 4 production. CD1d is also known as R3G1