In enzymology, a cyclohexylamine oxidase (EC 1.4.3.12) is an enzyme that catalyzes the chemical reaction In enzymology, a cyclohexylamine oxidase (EC 1.4.3.12) is an enzyme that catalyzes the chemical reaction The 3 substrates of this enzyme are cyclohexylamine, O2, and H2O, whereas its 3 products are cyclohexanone, NH3, and H2O2. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is cyclohexylamine:oxygen oxidoreductase (deaminating). This enzyme participates in caprolactam degradation. It employs one cofactor, FAD.