Subarachnoid space

The meninges (/məˈnɪndʒiːz/, singular: meninx (/ˈmiːnɪŋks/ or /ˈmɛnɪŋks/), from Ancient Greek: μῆνιγξ, romanized: mēninx, lit. 'membrane', adjectival: meningeal /məˈnɪndʒəl/) are the three membranes that envelop the brain and spinal cord. In mammals, the meninges are the dura mater, the arachnoid mater, and the pia mater. Cerebrospinal fluid is located in the subarachnoid space between the arachnoid mater and the pia mater. The primary function of the meninges is to protect the central nervous system.Illustration of the work by Antonio Pacchioni Disquisitio anatomicae de durae meningis ... published in Acta Eruditorum, 1703 The meninges (/məˈnɪndʒiːz/, singular: meninx (/ˈmiːnɪŋks/ or /ˈmɛnɪŋks/), from Ancient Greek: μῆνιγξ, romanized: mēninx, lit. 'membrane', adjectival: meningeal /məˈnɪndʒəl/) are the three membranes that envelop the brain and spinal cord. In mammals, the meninges are the dura mater, the arachnoid mater, and the pia mater. Cerebrospinal fluid is located in the subarachnoid space between the arachnoid mater and the pia mater. The primary function of the meninges is to protect the central nervous system. The dura mater (Latin: tough mother) (also rarely called meninx fibrosa or pachymeninx) is a thick, durable membrane, closest to the skull and vertebrae. The dura mater, the outermost part, is a loosely arranged, fibroelastic layer of cells, characterized by multiple interdigitating cell processes, no extracellular collagen, and significant extracellular spaces. The middle region is a mostly fibrous portion. It consists of two layers: the endosteal layer, which lies closest to the calvaria (skullcap), and the inner meningeal layer, which lies closer to the brain. It contains larger blood vessels that split into the capillaries in the pia mater. It is composed of dense fibrous tissue, and its inner surface is covered by flattened cells like those present on the surfaces of the pia mater and arachnoid mater. The dura mater is a sac that envelops the arachnoid mater and surrounds and supports the large dural sinuses carrying blood from the brain toward the heart.