Reticulocalbin 1

595419672ENSG00000049449ENSMUSG00000005973Q15293Q05186NM_002901NM_009037NP_002892NP_033063Reticulocalbin-1 is a protein that in humans is encoded by the RCN1 gene. Reticulocalbin-1 is a protein that in humans is encoded by the RCN1 gene. Reticulocalbin 1 is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. High conservation of amino acid residues outside of these motifs, in comparison to mouse reticulocalbin, is consistent with a possible biochemical function besides that of calcium binding.