Cianopramine (INN) (developmental code name Ro 11-2465), also known as 3-cyanoimipramine, is a tricyclic antidepressant related to imipramine that acts as a serotonin reuptake inhibitor and weak serotonin receptor antagonist. It was investigated for the treatment of depression but was never marketed. Cianopramine (INN) (developmental code name Ro 11-2465), also known as 3-cyanoimipramine, is a tricyclic antidepressant related to imipramine that acts as a serotonin reuptake inhibitor and weak serotonin receptor antagonist. It was investigated for the treatment of depression but was never marketed.