Phosphoramide

Phosphoramide is a chemical compound with the molecular formula P(=O)(NH2)3. It is a derivative of phosphoric acid in which each of the hydroxyl groups have been replaced with an amino group. Phosphoramide arises from the reaction of phosphoryl chloride with ammonia. It is a white solid that is soluble in polar solvents. In moist air, it hydrolyzes to an ammonium salt: Phosphoramide is a chemical compound with the molecular formula P(=O)(NH2)3. It is a derivative of phosphoric acid in which each of the hydroxyl groups have been replaced with an amino group. Phosphoramide arises from the reaction of phosphoryl chloride with ammonia. It is a white solid that is soluble in polar solvents. In moist air, it hydrolyzes to an ammonium salt: It reacts with sodium hydroxide with loss of ammonia: The related thiophosphoryl compound P(=S)(NH2)3 was made from the reaction of thiophosphoryl chloride with ammonia. Phosphoramide is also the parent compound for a range of derivatives called phosphoramides. An example compound is the polar solvent hexamethylphosphoramide (HMPA).