Atomic mass constant

The dalton or unified atomic mass unit (SI symbols: Da or u) is a unit of mass widely used in physics and chemistry. It is defined precisely as 1/12 of the mass of an unbound neutral atom of carbon-12 in its nuclear and electronic ground state and at rest. A mass of 1 Da is also referred to as the atomic mass constant and denoted by mu.with NA The dalton or unified atomic mass unit (SI symbols: Da or u) is a unit of mass widely used in physics and chemistry. It is defined precisely as 1/12 of the mass of an unbound neutral atom of carbon-12 in its nuclear and electronic ground state and at rest. A mass of 1 Da is also referred to as the atomic mass constant and denoted by mu. This unit is commonly used in physics and chemistry to express the mass of atomic-scale objects, such as atoms, molecules, and elementary particles, both for discrete instances and multiple types of ensemble averages. For example, an atom of helium-4 has a mass of 4.0026 Da. This is an intrinsic property of the isotope and all helium-4 have the same mass. Acetylsalicylic acid (aspirin), C9H8O4, has an average mass of approximately 180.157 Da. However, there are no acetylsalicylic acid molecules with this mass. The two most common masses of individual acetylsalicylic acid molecules are 180.04228 Da and 181.04565 Da. The molecular masses of proteins, nucleic acids, and other large polymers are often expressed with the units kilodaltons (kDa), megadaltons (MDa), etc. Titin, one of the largest known proteins, has a molecular mass of between 3 and 3.7 megadaltons. The DNA of chromosome 1 in the human genome has about 249 million base pairs, each with an average mass of about 650 Da, or 156 GDa total. The mole is a unit of amount of substance, widely used in chemistry and physics, which was originally defined so that the mass of one mole of a substance, measured in grams, would be numerically equal to the average mass of one of its constituent particles, measured in daltons. That is, the molar mass of a chemical compound was meant to be numerically equal to its average molecular mass. For example, the average mass of one molecule of water is about 18.0153 daltons, and one mole of water is about 18.0153 grams. A protein whose molecule has an average mass of 64 kDa would have a molar mass of 64 kg/mol. However, while this equality can be assumed for almost all practical purposes, it is now only approximate, because of the way mole was redefined on 20 May 2019. The mass in daltons of an atom is numerically close to the number of nucleons A in its nucleus. It follows that the molar mass of a compound (grams per mole) is also numerically close to the average number of nucleons per molecule. However, the mass of an atomic-scale object is affected by the binding energy of the nucleons in its atomic nuclei, as well as the mass and binding energy of the electrons. Therefore, this equality holds only for the carbon-12 atom in the stated conditions, and will vary for other substances. For example, the mass of one unbound atom of the common hydrogen isotope (hydrogen-1, protium) is 1.007825032241(94) Da, the mass of one free neutron is 1.008664915823(491) Da, and the mass of one hydrogen-2 (deuterium) atom is 2.014101778114(122) Da. In general, the difference (mass defect) is less than 0.1%; except for hydrogen (about 0.8%), helium-3 (0.5%), lithium (0.25%) and beryllium (0.15%). The atomic mass unit should not be confused with unit of mass in the atomic units systems, which is instead the electron rest mass (me). The atomic mass constant can also be expressed as its energy equivalent, that is muc2. The 2018 CODATA recommended values are: The megaelectronvolt (MeV) is commonly used as a unit of mass in particle physics, and these values are also important for the practical determination of relative atomic masses. The interpretation of the law of definite proportions in term of the atomic theory of matter implied that the masses of atoms of various elements had definite ratios that depended on the elements. While the actual masses were unknown, the relative masses could be deduced from that law. In 1803 John Dalton proposed to use the (still unknown) atomic mass of the lightest atom, that of hydrogen, as the natural unit of atomic mass. This was the basis of the atomic weight scale.