CYP2A13

2P85, 2PG5, 2PG6, 2PG7, 3T3S, 4EJG, 4EJH, 4EJI155313087ENSG00000197838ENSMUSG00000005547Q16696P20852NM_000766NM_007812NP_000757n/aCytochrome P450 2A13 is a protein that in humans is encoded by the CYP2A13 gene.1z10: Crystal Structure of Human Microsomal P450 2A6 with Coumarin Bound1z11: Crystal Structure of Human Microsomal P450 2A6 with Methoxsalen Bound2fdu: Microsomal P450 2A6 with the inhibitor N,N-Dimethyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound2fdv: Microsomal P450 2A6 with the inhibitor N-Methyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound2fdw: Crystal Structure Of Human Microsomal P450 2A6 with the inhibitor (5-(Pyridin-3-yl)furan-2-yl)methanamine bound2fdy: Microsomal P450 2A6 with the inhibitor Adrithiol bound2p85: Structure of Human Lung Cytochrome P450 2A13 with indole bound in two alternate conformations Cytochrome P450 2A13 is a protein that in humans is encoded by the CYP2A13 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.