3,4-Dihydroxyphenylacetaldehyde

Phenylglyoxal3,4-Dihydroxyphenylacetaldehyde (DOPAL) is an important metabolite of the major brain neurotransmitter dopamine. All of the enzymatic metabolism of dopamine in neurons passes through DOPAL. According to the 'catecholaldehyde hypothesis,' DOPAL plays a role in the pathogenesis of Parkinson's Disease. DOPAL has been chemically synthesized. DOPAL is detoxified mainly by aldehyde dehydrogenase. 3,4-Dihydroxyphenylacetaldehyde (DOPAL) is an important metabolite of the major brain neurotransmitter dopamine. All of the enzymatic metabolism of dopamine in neurons passes through DOPAL. According to the 'catecholaldehyde hypothesis,' DOPAL plays a role in the pathogenesis of Parkinson's Disease. DOPAL has been chemically synthesized. DOPAL is detoxified mainly by aldehyde dehydrogenase.