RAB7B

338382226421ENSG00000276600ENSMUSG00000052688Q96AH8Q8VEA8NM_001164522NM_001304839NM_177403NM_145509NM_001311096NP_001157994NP_001291768NP_796377NP_001298025NP_663484Ras-related protein Rab-7b is a protein that in humans is encoded by the RAB7B gene. Ras-related protein Rab-7b is a protein that in humans is encoded by the RAB7B gene. Rab7 is a small GTPase that plays a role in the transport and degradation of proteins in endosomes and lysosomes in mammalian cells. Rab7b, is localized to lysosome-associated compartments and is selectively expressed in monocytic cells. By promoting the degradation of toll-like receptor 4, RAB7B can negatively regulate the inflammatory activation of macrophages.