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Haplogroup CT

Haplogroup CT is a human Y chromosome haplogroup, defining one of the major paternal lineages of humanity. Haplogroup CT is a human Y chromosome haplogroup, defining one of the major paternal lineages of humanity. Men who carry the CT clade have Y chromosomes with the SNP mutation M168, along with P9.1 and M294. These mutations are present in all modern human male lineages except A and B-M60, which are both found almost exclusively in Africa. The most recent common male line ancestor (TMRCA) of all CT men today probably predated the recent African origin of modern humans, a migration in which some of his descendants participated. He is therefore thought to have lived in Africa before this proposed migration. In keeping with the concept of 'Y-chromosomal Adam' given to the patrilineal ancestor of all living humans, CT-M168 has therefore also been referred to in popularized accounts as being the lineage of 'Eurasian Adam' or 'Out of Africa Adam'. No male in paragroup CT* has ever been discovered in modern populations. This means that all males carrying this haplogroup are also defined as being in one of the several major branch clades. All known surviving descendant lineages of CT are in one of two major subclades, CF and DE. In turn, DE is divided into an Asia-distributed haplogroup D-M174 and a predominantly Africa-distributed haplogroup E-M96, while CF is divided into an East Asian, American, and Oceanian haplogroup C-M130 and haplogroup F-M89, which dominates most non-African populations. Haplogroup CT had been found in various prehistoric human fossils that were analysed for ancient DNA, including specimens associated with the Pre-Pottery Neolithic C (1/1; 100%), Neolithic Ganj Dareh Iran (1/2 50%), Natufian (2/5; 40%), Pre-Pottery Neolithic B (2/7; ~29%), Alföld Linear Pottery (1/1 at two ALP archaeological sites; 100%), Linearbandkeramik (1/2 at Karsdorf LBK archaeological site; 50%) cultures, and some Upper Paleolithic Europeans (Cioclovina1, Kostenki12, Vestonice13). But whether these, or all of them, belong to paragroup CT* or to its branches, is as yet undetermined.

[ "Single-nucleotide polymorphism", "Haplotype", "Y chromosome" ]
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