MERTK

2DBJ, 2P0C, 3BPR, 3BRB, 3TCP, 4M3Q, 4MH7, 4MHA1046117289ENSG00000153208ENSMUSG00000014361Q12866Q60805NM_006343NM_008587NP_006334NP_032613Proto-oncogene tyrosine-protein kinase MER is an enzyme that in humans is encoded by the MERTK gene.2dbj: Solution structures of the fn3 domain of human Proto-oncogene tyrosine-protein kinase MER precursor2p0c: Catalytic Domain of the Proto-oncogene Tyrosine-protein Kinase MER Proto-oncogene tyrosine-protein kinase MER is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the TYRO3/AXL/MER (TAM) receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).