Seminiferous tubule

Seminiferous tubules are located within the testes, and are the specific location of meiosis, and the subsequent creation of male gametes, namely spermatozoa.Seminiferous tubule (right) with sperm (black, tiny, ovoid). H&E stain.Longitudinal section through the left side of the scrotum and the left testis (Seminiferous tubules visible in center, but not labeled).Seminiferous tubule (transverse section).Photomicrograph of section through rat testis, showing seminiferous tubules. Seminiferous tubules are located within the testes, and are the specific location of meiosis, and the subsequent creation of male gametes, namely spermatozoa. The epithelium of the tubule consists of a type of sustentacular cells known as Sertoli cells, which are tall, columnar type cells that line the tubule. In between the Sertoli cells are spermatogenic cells, which differentiate through meiosis to sperm cells. Sertoli cells function to nourish the developing sperm cells. They secrete androgen-binding protein, a binding protein which increases the concentration of testosterone inside the seminiferous tubules. Embryologically, they also secrete the anti-Müllerian hormone (AMH) necessary for the female Müllerian ducts to regress.