2BBU, 2HMH, 2JZ3, 4GL9902112702ENSG00000184557ENSMUSG00000053113O14543Q6FI39O35718NM_003955NM_007707NP_003946NP_003946.3NP_031733Suppressor of cytokine signaling 3 (SOCS3 or SOCS-3) is a protein that in humans is encoded by the SOCS3 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling.2bbu: solution structure of mouse socs3 in complex with a phosphopeptide from the gp130 receptor Suppressor of cytokine signaling 3 (SOCS3 or SOCS-3) is a protein that in humans is encoded by the SOCS3 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling.