1FZV, 1RV6522818654ENSG00000119630ENSMUSG00000004791P49763P49764NM_002632NM_001207012NM_001293643NM_001271705NM_008827NP_001193941NP_001280572NP_002623NP_001258634NP_032853Placental growth factor is a protein that in humans is encoded by the PGF gene.1rv6: Crystal Structure of PlGF in Complex with Domain 2 of VEGFR1 Placental growth factor is a protein that in humans is encoded by the PGF gene. Placental growth factor (PGF) is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast.