Oragene

Oragene was invented by Dr. H. Chaim Birnboim. The basis for Oragene is outlined in his 1979 paper which described the widely used method of alkaline extraction of plasmid DNA from bacteria. For the first time, genetic researchers had access to a mechanism to collect large amounts of high quality DNA through non-invasive sampling. Prior to this discovery, the only option for those with this requirement was to use blood samples. Oragene allows donors to spit into a plastic tube to provide a reliable, high quality DNA sample in a non-invasive way. Oragene is used by academic research institutions, bone marrow donor registries, hospitals, clinical testing laboratories, and direct-to-consumer genetic testing companies who require large amounts of high quality DNA from a large number of donors. The non-invasive collection method offered by Oragene allows collection of DNA from those who might be unwilling to provide a blood sample. In addition, Oragene can be sent via the standard postal system providing the ability for customers to scale their operations on a global basis. Oragene can be used to collect more samples from patients and donors with at-home or in-office point-of-care DNA collection. Oragene is compatible with a variety of downstream applications including microarrays and next generation sequencing. Oragene is referenced in over 1100 peer-reviewed scientific journals including the following: