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GAB1

4QSY254914388ENSG00000109458ENSMUSG00000031714Q13480Q9QYY0NM_002039NM_207123NM_001301298NM_021356NP_002030NP_997006NP_001288227NP_067331GRB2-associated-binding protein 1 is a protein that in humans is encoded by the GAB1 gene. GRB2-associated-binding protein 1 is a protein that in humans is encoded by the GAB1 gene. The protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. The encoded protein is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. GAB1 has been shown to interact with:

[ "Protein kinase B", "PI3K/AKT/mTOR pathway", "Receptor tyrosine kinase", "Tyrosine phosphorylation", "GRB2" ]
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