DNM1

1DYN, 2DYN, 2X2E, 2X2F, 3SNH, 3ZYC, 3ZYS, 4UUD, 4UUK, 5D3Q175913429ENSG00000106976ENSMUSG00000026825Q05193P39053NM_001005336NM_001288737NM_001288738NM_001288739NM_004408NM_001301737NM_010065NM_001368679NP_001005336NP_001275666NP_001275667NP_001275668NP_004399NP_001288666NP_034195NP_001355608Dynamin-1 is a protein that in humans is encoded by the DNM1 gene.1dyn: CRYSTAL STRUCTURE AT 2.2 ANGSTROMS RESOLUTION OF THE PLECKSTRIN HOMOLOGY DOMAIN FROM HUMAN DYNAMIN2aka: Structure of the nucleotide-free myosin II motor domain from Dictyostelium discoideum fused to the GTPase domain of dynamin 1 from Rattus norvegicus2dyn: DYNAMIN (PLECKSTRIN HOMOLOGY DOMAIN) (DYNPH) Dynamin-1 is a protein that in humans is encoded by the DNM1 gene. This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. DNM1 has been shown to interact with: