ADH4

3COS12726876ENSG00000198099ENSMUSG00000037797P08319Q9QYY9NM_000670NM_001306171NM_001306172NM_011996NP_000661NP_001293100NP_001293101NP_036126Alcohol dehydrogenase 4 is an enzyme that in humans is encoded by the ADH4 gene. Alcohol dehydrogenase 4 is an enzyme that in humans is encoded by the ADH4 gene. This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.