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Molecular promiscuity

Molecular promiscuity indicates the ability of a molecule to bind to interact with one or more other classes and subtypes of molecules, in synergistic or antagonistic ways. These interactions may involve multiple paracrine, endocrine and autocrine features. Essentially, the more promiscuous a molecule is, the more readily it may be able to interact with other molecules (i.e. a cytokines like IL-2 may interact with many other proliferation signals and cells to induce that response). Molecular promiscuity indicates the ability of a molecule to bind to interact with one or more other classes and subtypes of molecules, in synergistic or antagonistic ways. These interactions may involve multiple paracrine, endocrine and autocrine features. Essentially, the more promiscuous a molecule is, the more readily it may be able to interact with other molecules (i.e. a cytokines like IL-2 may interact with many other proliferation signals and cells to induce that response).

[ "Drug discovery", "Cancer", "Polypharmacology" ]
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