Rate of infusion

In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective. In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective. Abbreviations include Kin, K0, or R0. It can be calculated as the steady-state concentration in the plasma multiplied by the clearance: K i n = C s s ⋅ C L {displaystyle extstyle K_{in}=C_{ss}cdot CL}