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Hesperadin

Hesperadin is an aurora kinase inhibitor. Hesperadin is an aurora kinase inhibitor. The small molecule inhibits chromosome alignment and segregation by limiting the function of miotic kinases Aurora B and Aurora A Hesperadin causes cells to enter Anaphase much faster, sometimes before the chromosomes are properly mono-oriented. Hesperadin, like other miotic inhibitors, limits and sometimes can stop the process of mitosis in cells. For this reason, some have considered Hesperadin’s potential as a cancer-preventing drug. Hesperadin works as an inhibitor, attaching to the active sites of Aurora A and Aurora B kinases.

[ "Cell cycle", "Cytokinesis", "Kinetochore", "Chromosome segregation", "Aurora inhibitor" ]
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