Cleo is a given name that is short for Cleopatra or Cleophus and an alternate spelling of Clio. It is a Greek prefix often translated to mean 'pride', 'fame' or 'glory'. Cleo is a given name that is short for Cleopatra or Cleophus and an alternate spelling of Clio. It is a Greek prefix often translated to mean 'pride', 'fame' or 'glory'. Cleo may refer to: