Mediodorsal nucleus

The medial dorsal nucleus (or dorsomedial nucleus of thalamus) is a large nucleus in the thalamus.It relays inputs from the amygdala and olfactory cortex and projects to the prefrontal cortex and the limbic system and in turn relays them to the prefrontal association cortex. As a result, it plays a crucial role in attention, planning, organization, abstract thinking, multi-tasking, and active memory.While both the ventral and medial dorsal nuclei process pain, the medial dorsal nucleus bypasses primary cortices, sending their axons directly to secondary and association cortices. The cells also send axons directly to many parts of the brain, including nuclei of the limbic system such as the lateral nucleus of the amygdala, the anterior cingulate, and the hippocampus. This part of the sensory system, known as the non-classical or extralemniscal system is less accurate, and less detailed in regards to sensory signal analysis. This processing is known colloquially as 'fast and dirty' rather than the 'slow and accurate' system of classical or lemniscal system. This pathway activates parts of the brain that evoke emotional responses.Damage to the medial dorsal nucleus has been associated with Korsakoff's syndrome.ThalamusThalamus