ABCC4

10257239273ENSG00000125257ENSMUSG00000032849O15439n/aNM_001105515NM_001301829NM_001301830NM_005845NM_001033336NM_001163675NM_001163676NP_001098985NP_001288758NP_001288759NP_005836n/aATP-binding cassette sub-family C member 4 (ABCC4), also known as the multidrug resistance-associated protein 4 (MRP4) or multi-specific organic anion transporter B (MOAT-B), is a protein that in humans is encoded by the ABCC4 gene. ATP-binding cassette sub-family C member 4 (ABCC4), also known as the multidrug resistance-associated protein 4 (MRP4) or multi-specific organic anion transporter B (MOAT-B), is a protein that in humans is encoded by the ABCC4 gene. ABCC4 acts as a regulator of intracellular cyclic nucleotide levels and as a mediator of cAMP-dependent signal transduction to the nucleus. MRP4/ABCC4 also transports prostaglandins, for example PGE2, out of the cell where they can bind receptors. MRP4/ABCC4 expression is dysregulated in several cancers and is also upregulated in peritoneal endometriosis. Click on genes, proteins and metabolites below to link to respective articles.