Adenophostin

Adenophostin A is a potent inositol trisphosphate (IP3) receptor agonist, but is much more potent than IP3. Adenophostin A is a potent inositol trisphosphate (IP3) receptor agonist, but is much more potent than IP3. IP3R is a ligand-gated intracellular Ca2+ release channel that plays a central role in modulating cytoplasmic free Ca2+ concentration (Ca2+i). Adenophostin A is structurally different from IP3 but could elicit distinct calcium signals in cells.