1E4U, 1UR6485053621ENSG00000080802ENSMUSG00000038784O95628Q8BT14NM_013316NM_001164411NM_001164412NM_001164413NM_001164414NM_016877NP_037448NP_001157883NP_001157884NP_001157885NP_001157886NP_058573CCR4-NOT transcription complex, subunit 4 is a protein that in humans is encoded by the CNOT4 gene. CCR4-NOT transcription complex, subunit 4 is a protein that in humans is encoded by the CNOT4 gene. The protein encoded by this gene is a subunit of the CCR4-NOT complex, a global transcriptional regulator. The encoded protein interacts with CNOT1 and has E3 ubiquitin ligase activity. Several transcript variants encoding different isoforms have been found for this gene.. Diseases associated with CNOT4 include Adenoiditis. This article incorporates text from the United States National Library of Medicine, which is in the public domain.