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Chemical castration

Chemical castration is castration via anaphrodisiac drugs, whether to reduce libido and sexual activity, to treat cancer, or otherwise. Unlike surgical castration, where the gonads are removed through an incision in the body, chemical castration does not remove organs, nor is it a form of sterilization. Chemical castration is generally considered reversible when treatment is discontinued, although permanent effects in body chemistry can sometimes be seen, as in the case of bone density loss increasing with length of use of DMPA. Chemical castration is castration via anaphrodisiac drugs, whether to reduce libido and sexual activity, to treat cancer, or otherwise. Unlike surgical castration, where the gonads are removed through an incision in the body, chemical castration does not remove organs, nor is it a form of sterilization. Chemical castration is generally considered reversible when treatment is discontinued, although permanent effects in body chemistry can sometimes be seen, as in the case of bone density loss increasing with length of use of DMPA. In May 2016, The New York Times reported that a number of countries use chemical castration on sex offenders, often in return for reduced sentences. When used on males, these drugs can reduce sex drive, compulsive sexual fantasies, and capacity for sexual arousal. Life-threatening side effects are rare, but some users show increases in body fat and reduced bone density, which increase long-term risk of cardiovascular disease and osteoporosis. They may also experience gynecomastia (development of larger-than-normal mammary glands in males). When used on females, the effects are similar, though there is little research about chemically lowering females's sex drive or female-specific anaphrodisiacs, since most research focuses on the opposite, but anti-androgenic hormone regimens would lower testosterone in females which can impact sex drive or sexual response. These drugs also deflate the breast glands and expand the size of the nipple. Also seen is a sudden shrinking in bone mass and discoloration of the lips, reduced body hair, and muscle mass. The first use of chemical castration occurred in 1944, when diethylstilbestrol was used with the purpose of lowering men's testosterone.The antipsychotic agent benperidol is sometimes used to diminish sexual urges in people who display inappropriate sexual behavior, and can likewise be given by depot injection. But benperidol does not affect testosterone and is therefore not a castration agent.Chemical castration is often seen as an easier alternative to life imprisonment or the death penalty because it allows the release of sex offenders while reducing or eliminating the chance that they reoffend. In 1981, in an experiment by P. Gagne, 48 males with long-standing histories of sexually deviant behaviour were given medroxyprogesterone acetate for as long as 12 months. Forty of those subjects were recorded as to have diminished desires for deviant sexual behaviour, less frequent sexual fantasies, and greater control over sexual urges. The research recorded a continuation of this more positive behaviour after the administration of the drug had ended with no evidence of adverse side effects and recommended medroxyprogesterone acetate along with counselling as a successful method of treatment for serial sex offenders. Spaying is observed to cause female animals to stop mating in the same species as castration causes male animals to stop mating. However, in animal species where females continue their mating behaviour after being spayed, the males also continue to mate after being castrated. So there are scientists who argue that it makes no biological sense to assume that any treatment that emulates castration would remove sex drive in men but not in women. These scientists argue that these observations, along with the fact that humans are animals and subject to evolution, show that it is flawed to think that male sexuality would be treatable by medication if female sexuality is not. Some criminologists argue that the appearance of a lower recidivism rate in male sex offenders who take chemical castration treatment than in those who do not can be explained by factors other than biological effects of the medication. One hypothesis is that men who accept the negative effects of hormonal treatment in exchange for shorter prison sentence are distinct in that they value freedom from incarceration higher than men who rather stay in prison for a longer time than face the side effects of chemical castration. These criminologists explain apparently lower recidivism as an artifact of men who accept chemical castration being more engaged in hiding the evidence for reoffending, and that paroling such offenders constitute a risk of releasing criminals who commit as many new crimes as others but are better at hiding it. These criminologists also argue that police investigators treating castrated men as less likely to reoffend than non-castrated men may cause an investigation bias and self-fulfilling prophecy, and that men who sell some of their prescribed medicines on the black market for drugs get a hidden income that improve their ability to afford measures to hide recidivism that is not available to men without such prescriptions. Some neurologists acknowledge that testosterone plays a role in sexual arousal but that reducing sex drive will likely not reduce inappropriate sex behaviour. These researchers argue that since a weaker internal signal in the brain means a higher requirement for external stimulation to create a feedback loop that tires the brain circuits out as in orgasm and lead to satisfaction, a reduction of the internal stimulation from hormones would make the required external stimulation stronger and also more specific, as weaker signals involve narrower ranges of other brain functions in their loops. These scientists therefore argue that the biological (as opposed to sociological) effect of reduced testosterone is to make it more difficult and not easier to use masturbation without pornography or other socially acceptable substitutes to manage remaining sex drive in a former offender, and that many community persons (both male and female) find that a lower initial arousal makes it more difficult to orgasm by masturbation without pornography or with non-preferred stimulation.

[ "Testosterone", "Prostate cancer", "Castration" ]
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