Spot urine sample

Urine protein/creatinine ratio (UPCR) is a widely used initial method to estimate daily protein excretion in urine. Since the diagnosis and management of proteinuric renal diseases and the staging of chronic kidney disease (CKD) depend on accurate identification and quantitation of proteinuria, the implementation of the 24-hour urine collection is the most accurate procedure in practice to figure out the urinary protein excretion. However, in current clinical practice, UPCR is widely used to estimate daily protein excretion by virtue of its convenience and simplicity. Urine protein/creatinine ratio (UPCR) is a widely used initial method to estimate daily protein excretion in urine. Since the diagnosis and management of proteinuric renal diseases and the staging of chronic kidney disease (CKD) depend on accurate identification and quantitation of proteinuria, the implementation of the 24-hour urine collection is the most accurate procedure in practice to figure out the urinary protein excretion. However, in current clinical practice, UPCR is widely used to estimate daily protein excretion by virtue of its convenience and simplicity. The difference between UPCR and 24-hour (24h) urine collection is that UPCR's sample is collected at a random time which is called Random urine sample, untimed urine sample or spot urine sample. Furthermore, UPCR is a ratio of total protein in urine at a random time and creatinine present in the urine at the random time . is taken into account due to the notion that creatinine is normally released into the urine at a constant rate.Scientists found that the ratio of protein and creatinine (denoted as protein/creatinine) roughly estimates the actual value gained from the 24-hour urine protein test. The normal UPCR is not more than 200 mg/g.