language-icon Old Web
English
Sign In

Neutralizing antibody

A neutralizing antibody (NAb) is an antibody that defends a cell from an antigen or infectious body by neutralizing any effect it has biologically. An example of a neutralizing antibody is diphtheria antitoxin, which can neutralize the biological effects of diphtheria toxin.'Antibodies can simply bind to IFN-beta or glatiramer acetate (binding Ab, or BAb) with no subsequent effect on function, or they can block or neutralize (neutralizing Ab, or NAb) their biological activity.' --Mark S. Freedman, MD, MSc A neutralizing antibody (NAb) is an antibody that defends a cell from an antigen or infectious body by neutralizing any effect it has biologically. An example of a neutralizing antibody is diphtheria antitoxin, which can neutralize the biological effects of diphtheria toxin. Most antibodies work by binding to an antigen, signaling to a white blood cell that this antigen has been targeted, after which the antigen is processed and consequently destroyed. The difference between neutralizing antibodies and binding antibodies is that neutralizing antibodies neutralize the biological effects of the antigen, while binding antibodies flag antigens. This difference can be shown with IFN-beta (IFN-β); This difference is what gives neutralizing antibodies the ability to fight viruses which attack the immune system, since they can neutralize function without a need for white blood cells (excluding production)

[ "Immune system", "Antibody", "Virus", "Titer", "Silverwater virus", "Microneutralization Assay", "Virus-neutralizing Antibody", "Rotavirus IgG", "Xentuzumab" ]
Parent Topic
Child Topic
    No Parent Topic