Granulibacter bethesdensis

Granulibacter bethesdensis is a Gram-negative, aerobic coccobacillus to rod-shaped, non-motile, catalase-positive and oxidase-negative bacteria first described in 2006 by Dr. Steve Holland's team at the National Institutes of Health in Bethesda, Maryland. Granulibacter bethesdensis was identified in a series of patients with chronic granulomatous disease (CGD). In a later study, nearly half of patients with CGD tested and a quarter of healthy volunteers showed some immunoreactivity to Granulibacter bethesdensis, suggesting infections with this organism occur more often than it is isolated.