Poikilocytosis

Poikilocytosis is variation in cell shape: poikilocytes may be oval, teardrop-shaped, sickle-shaped or irregularly contracted. Poikilocytosis is variation in cell shape: poikilocytes may be oval, teardrop-shaped, sickle-shaped or irregularly contracted. Normal red blood cells are round, flattened disks that are thinner in the middle than at the edges. A poikilocyte is an abnormally shaped cell. Generally, poikilocytosis can refer to an increase in abnormal red blood cells of any shape where they make up 10% or more of the total population.