CRMP1

4B3Z140012933ENSG00000072832ENSMUSG00000029121Q14194P97427NM_001313NM_001014809NM_001288661NM_001288662NM_001136058NM_007765NP_001014809NP_001275590NP_001275591NP_001304NP_001129530NP_031791Collapsin response mediator protein 1, encoded by the CRMP1 gene, is a human protein of the CRMP family.1kcx: X-ray structure of NYSGRC target T-45 Collapsin response mediator protein 1, encoded by the CRMP1 gene, is a human protein of the CRMP family. This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants. CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory. CRMP1 gene overlaps with another gene called EVC. CRMP1 has been shown to interact with DPYSL2.