EIF5A

3CPF, 5DLQ1984276770ENSG00000132507ENSMUSG00000078812P63241P63242NM_001370421NM_001166594NM_001166595NM_001166596NM_181582NP_001357350NP_001160066NP_001160067NP_001160068NP_853613Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene. Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene. It is the only known protein to contain the unusual amino acid hypusine , which is synthesized on eIF5A at a specific lysine residue from the polyamine spermidine by two catalytic steps. EF-P is the prokaryotic homolog of eIF5A, which is also modified post-translationally in a similar but distinct way.