RELT

84957320100ENSG00000054967ENSMUSG00000008318Q969Z4Q8BX43NM_032871NM_152222NM_177073NM_001358914NP_116260NP_689408NP_796047NP_001345843Tumor necrosis factor receptor superfamily member 19L is a protein that in humans is encoded by the RELT gene. Tumor necrosis factor receptor superfamily member 19L is a protein that in humans is encoded by the RELT gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.