Les phénotypes Hm récessifs

Summary The survival of « Bombayerythrocytes as well as that of « para Bombayred cells (first and third class according to Race and Sanger classification) has been studied among non compatible and « para Bombayindividuals. This shows not only the heterogeneity of these phenotypes (as already described by Salmon and co workers) but also the presence of highly differenciated ABH formed antigens. H deficient recessive phenotypes are not explained by the presence of an amorphe h gene. They arise from the activity (or better from the non activity) of the regulation genes of which the recessive alleles x and z in double dose do not enable a normal functioning of the H gene. The appelation H xx for « Bombayphenotypes (1st classe) and the appelation H zz for Hm recessive (3d. class) phenotypes are proposed. Genetics as well as the synthesis of A h , B h (A Hm , B Hm ) phenotypes have not yet been clarified. Interaction of zz and sese genes, or accomplementation in the « transposition have to be looked at.