Application of synchrotron radiation in chemistry--status and future

from a “waste product” of high-energy physics to a unique excitation radiation source for diverse methods, which – in the broadest sense – are based on the interaction of electromagnetic radiation with matter. The basis is the broad continuous spectrum from infrared to the hard X-ray field, the very high intensity of radiation (which is not achievable otherwise), its polarization of almost 100, and the interesting time structure. 20 years ago, physicists started to develop and provide sources that were specifically designed for the needs of the method’s developers and users. The third generation is in operation worldwide, while the fourth generation, which offers far better possibilities, is in the development stage with the use of free electron lasers. In many cases, the methods using synchrotron radiation as excitation source have reached development status, which allows their routine, service-orientated application. Meanwhile, they are used even for screening studies, e.g., in polymer research and proteomics. Several sources are especially targeted toward synchrotron radiation and offer widely standardized conditions; others are more scientifically orientated and offer more flexible possibilities. Worldwide – and in particular in Europe – a complex spectrum of application possibilities exists, offering many possibilities, especially in chemistry. The Hamburg workshop “Applications of synchrotron radiation in chemistry – status and future” that took place on September 16–17, 2002, offered an overview of the methods established in chemistry, and their application areas. In the present special issue, “Synchrotron Radiation” of Analytical and Bioanalytical Chemistry, selected and particularly current examples are presented. We thank Springer-Verlag for the possibility to coherently demonstrate, to a broad readership, the importance of synchrotron radiation for the different areas of chemistry, and thus to present a novel field of activity of analytical chemistry that is becoming more and more important. May this special issue stimulate as many expert colleagues as possible to use synchrotron radiation and the analytical methods based on it. Arndt Knochel