And a process for preparing compounds having analgesic effect

The present invention discloses a method of preparing compounds and have an analgesic effect, the compound of the structural formula below Ⅰ, Ⅱ, Ⅲ or IV shown, wherein, R is a linear alkyl group of the formula CnH2n + 1 is, n = 1-7. The present invention also discloses a method for preparing the above-described several different structures of the compounds of formula, and their use in the manufacture of a capsaicin receptor inhibitors. The present invention provides a compound having a strong analgesic activity, over part of pethidine, and pharmacological experiments such compounds is found addictive side effects. The present invention provides compounds plus a pharmaceutically acceptable carrier can be prepared into pharmaceutical formulations and pharmaceutical compositions can be developed and prepared in non-analgesic drugs of addiction.