The Influence of the Cholesterol Level in Cells on Endovanilloid Cytotoxicity.

M. G. Akimov,P V Dudina,A. M. Gamisonia,Natalia Gretskaya,G. N. Zinchenko,C. C. Mandal,Vladimir V. Bezuglov

The Influence of the Cholesterol Level in Cells on Endovanilloid Cytotoxicity.

2020

M. G. Akimov
P V Dudina
A. M. Gamisonia
Natalia Gretskaya
G. N. Zinchenko
C. C. Mandal
Vladimir V. Bezuglov

The influence of the cellular cholesterol content on the cytotoxicity of endovanilloids acyldopamines was studied in MDA-MB-231 and MCF 10A cells. The activity of acyldopamines depends on the cellular cholesterol content, and a decrease in cholesterol content increases the cytotoxicity of acyldopamines.

Keywords:

cellular cholesterol
Chemistry
Endocannabinoid system
Cholesterol
Cytotoxicity
Pharmacology

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