Distinct Orchestration and Dynamic Processes on γ-H2AX and p-H3 for Two Major Types of Genotoxic Chemicals Revealed by Mass Spectrometry Analysis.

Minmin Qu,Hua Xu,Jia Chen,Yajiao Zhang,Bin Xu,Lei Guo,Jianwei Xie

Distinct Orchestration and Dynamic Processes on γ-H2AX and p-H3 for Two Major Types of Genotoxic Chemicals Revealed by Mass Spectrometry Analysis.

2020

Minmin Qu
Hua Xu
Jia Chen
Yajiao Zhang
Bin Xu
Lei Guo
Jianwei Xie

Genotoxic chemicals act by causing DNA damage, which, if left unrepaired, can have deleterious consequences for cell survival. DNA damage response (DDR) gets activated to repair or mitigate the eff...

Keywords:

Mass spectrometry
Orchestration (computing)
Organic chemistry
Chemistry
Aneugen
DNA Damage Repair
Biochemistry
Liquid chromatography–mass spectrometry
cell survival
Clastogen
DNA damage

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