Synthesis of some monosaccharide-related ester derivatives as insecticidal and acaricidal agents

Abstract To develop natural-product-based pesticidal agents, a series of monosaccharide-related ester derivatives ( 17a – q and 18a – f ), glucose (xylose)-piperic acid/piperic acid-like conjugates, were synthesized. Three-dimensional structures of compounds 17b , 17g , 17h , and 17n were unambiguously determined by single-crystal X-ray diffraction. Especially compounds 18e and 18f exhibited the most potent insecticidal and acaricidal activities against Mythimna separata and Tetranychus cinnabarinus . Their structure-activity relationships were also discussed.