Increased calcification in osteoprotegerin-deficient smooth muscle cells: Dependence on receptor activator of NF-κB ligand and interleukin 6.

Andrea Callegari,Matthew L. Coons,Jerry Ricks,Michael E. Rosenfeld,Marta Scatena

Increased calcification in osteoprotegerin-deficient smooth muscle cells: Dependence on receptor activator of NF-κB ligand and interleukin 6.

2014

Andrea Callegari
Matthew L. Coons
Jerry Ricks
Michael E. Rosenfeld
Marta Scatena

Objective: Vascular calcification is highly correlated with cardiovascular disease morbidity and mortality. Osteoprotegerin (OPG) is a secreted decoy receptor for

Keywords:

Anatomy
Osteoprotegerin
Calcification
Myocyte
RANK Ligand
Interleukin 6
NF-κB
Activator (genetics)
Biology
Internal medicine
Endocrinology
Receptor
RANKL
Vascular smooth muscle
Downregulation and upregulation

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