A convenient allylsilane-N-acyliminium route toward 5-alkylindolizidines. Diastereoselective synthesis of (±)-indolizidine 167B

Abstract A highly diastereoselective synthesis of 5-alkylindolizidines is described via an intermolecular addition of the allylsilyl functional group of homoallylic alcohols with an N -acyliminium ion derived from pyrrolidin-2-one.