N-azamonobactams. 2. Synthesis of some N-iminoacetic acid and N-glycyl analogues.

: The synthesis of the title compounds has been accomplished. The N-iminoacetic acid analogues (12a and 12b) containing the aminothiazole type side chain exhibited good in vitro antibacterial activity against Gram-negative organisms. The corresponding N-glycyl derivative (17) was not active.