Effects of Antiepileptic Drugs on Oxidative Stress Enzymes in Children with Epilepsy: Correlation with Child Psychopathology

Antiepileptic drugs (AEDs) used in children may affect the oxidative status and child psychopathology. Our study conducted to investigate the possible causal–effect relationship between commonly used AEDs, oxidative stress enzymes, and child psychopathology. Overall, 84 children with epilepsy, and 42 controls were assessed by child behavioral checklist and blood level of oxidative stress enzymes before and after 6 months use of AEDs. We reported significant statistical difference between patients before and after therapy regarding attention problems ( p -value  p -value